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KMID : 0363620090300010017
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Journal of Korean Oriental Medicine
2009 Volume.30 No. 1 p.17 ~ p.25
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Effect of the Combination of Total Saponin of Red Ginseng and Coisis Semen for the Prevention and Treatment of Obesity
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Kim In-Kyoung
Min Sang-Yeon
Kim Jang-Hyun
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Abstract
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Objectives: This study was on the pharmaceutical components in purified ginseng total saponin (GTS), coisis semen (CS), the combination of these drugs, and the major component of coicis coixol for the prevention and treatment of obesity.
Methods: In this study, to evaluate the effect on the suppression of obesity, high fat diet-induced obese rats were treating with the drugs, the effects on the balance of energy and diet activity were examined, and the change of weight, the change of the intake of diet, body fat rate, etc. were assessed.
Results: The results demonstrate that in high fat diet-induced obese white rats, the combination treatment of ginseng total saponin and coicis was effective in suppression of weight gain, reduction of intake of food, and reduction of body fat.
Conclusions: The results suggest that a combination treatment with major components of red ginseng total saponin and coicis may be used therapeutically for the suppression and treatment of obesity.
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KEYWORD
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Total saponin of red ginseng, coisis semen, coicis coixol, obesity
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